Leber Hereditary Optic Neuropathy: Do Folate Pathway Gene Alterations Influence the Expression of Mitochondrial DNA Mutation?

"nBackground: Leber hereditary optic neuropathy (LHON) is an inherited form of bilateral optic atrophy leading to the loss of central vision.  The primary cause of vision loss is mutation in the mitochondrial DNA (mtDNA), however, unknown secon­dary genetic and/or epigenetic risk factors are suggested to influence its neuropat

read more

Good Living as a Living Law

In 2008, Ecuador reformed its Constitution after a prolonged period of rico reserve clarinet mouthpiece economic, social and political crises.The momentary rupturing of power structures, that had limited political participation to small clusters of elites, opened participatory spaces for historically marginalised social groups to engage in the proc

read more

Comprehensive Genetic Analysis of Monokaryon and Dikaryon Populations Provides Insight Into Cross-Breeding of Flammulina filiformis

Flammulina filiformis, as one of the most popular edible fungi in East Asia, is produced in an industrialized and standardized way.However, its monotonous variety and product convergence have seriously restricted the development of the industry.In this study, 11 cultivated strains and 13 wild strains of F.filiformis were collected from short code 2

read more